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The UK’s Covid infection rate is rising. Here’s why

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Manchester City Soccer Club fans were seen wearing masks while watching the Premier League match between Manchester City FC and Burnley on October 16th, 2021.

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LONDON — When the Covid-19 pandemic swept the globe in 2020, the U.K. was hit hard, reporting some of the highest cases numbers and fatalities in Europe. However, the rapid vaccination program brought all cases under control.

The situation is now dramatically different. The country is recording close to 50,000 new Covid cases a day — meaning it has one of the worst daily infection rates in the world.

On MondayThere were 49,156 additional cases. It was the largest number of new cases recorded in just three months, bringing the total U.K. case count to more than 8.4million. The country also reported 45 new deaths within 28 days of a positive test, bringing the total number of fatalities to 138,629 — one of the highest death tolls in the world.

Hospitalizations and deaths continue to rise since July 19th, when Covid restrictions in England were lifted. The reopening of pubs, restaurants and nightclubs was followed by voluntary mask-wearing.

Continue readingThis is: England takes leap into the unknown, lifting Covid rules as cases surge

The number of deaths and hospitalizations has been declining at a slower pace than in earlier pandemics. This is due to the Covid vaccines’ high effectiveness at preventing serious infection and hospitalization.

However, experts in healthcare from the National Health Service warn that winter is coming.

Is there something going on?

Experts say there are a variety of reasons for the U.K.’s steep Covid numbers — ranging from the half-hearted mask adoption (even when masks are required, such as on public transport, the rule is rarely enforced) to large indoor gatherings that have allowed the virus to spread.

The U.K.’s hesitation to immunize younger adolescents, which was something other countries in Europe did earlier than the U.S., has been mentioned as a reason for the steep rise in cases. Data shows that infections are rising in the parents’ generation as well, but the U.K. is not vaccinating as many children as it used to.

In September 2021, people were seen outside dining in Soho (London) Covid restrictions have been lifted in the U.K. and people are returning to street, shops, public spaces, etc.

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Perhaps most ironically, the U.K.’s early vaccination rollout — which began in December 2020 and was one of the first in the world — is also seen as contributing to its high case rate now.

That’s because we now know — due to an increasing body of data — that immunity in vaccinated people wanes after about six months. It is believed that vaccine efficacy has been affected by the increased spread of delta Covid, a more contagious variant.

Dr. Eric Topol, founder and director of the Scripps Research Translational Institute, tweeted his assessment of the U.K.’s situationSamstag, the author stated: “Why do we currently have 6-folds hospital admissions in the UK and a 3x higher death rate than Europe?” One [the]There are two possible reasons. The first is that children aged 12-17 years have less exposure to mitigation measures.

As another contributing factor, he pointed out that the AstraZeneca vaccine’s effectiveness was declining slightly faster than Pfizer’s vaccine.

He suggested that “another possible explanation” is the fact that the U.K. was vaccinated later than other European countries and has shown more protection waning, particularly among seniors. Topol also noted that the U.K. did a better job than the U.S. in separating deaths from hospitalizations.

Based on what we know regarding waning immunity the U.K.like IsraelThe U.S.A. and other European countries) decided in September to roll out booster shotsFor those over 50, doctors and others with chronic conditions.

People who have had their booster shot at least six months prior to this one are asked to be the first. The NHS has administered a total of 3.6 million booster shots to date, which means that approximately 6.5 million English citizens are currently eligible for a booster. data shows

Experts have urged the government to increase vaccinations, especially in younger people. They also urged faster rollout of boosters. The experts also warn against complacency and relying on the government this winter. a controversial “herd immunity” strategy

Tim Spector: “The U.K. appears to slowly be waking up the fact that Covid case numbers are too high but they’ve been soaring since months, and many countries put us on the red list.” Professor of Genetic Epidemiology, King’s College London The ZOE COVID Study application, which analyses and collects Covid data from various sources, has a lead scientist, he noted last week.

“Infections remain high among young people and appear to be spreading over to the 35-55 age group.” He noted that if these cases rise to the 55-year-olds, it could be a disaster for the NHS. “With cases so high, it’s clear that herd immunity isn’t happening, and the risk is most people continue to believe they are safe if they have had Covid or a vaccine … We need to be doing all we can to get everyone double vaccinated and stop waiting for herd immunity to happen through natural infection.”

Beware of Variant Worries

It is becoming increasingly apparent that a descendant of the covid delta variant has been identified in an increasing amount of U.K. Covid case, some suggesting this could also be a factor in rising cases.

Last Friday,According to the U.K. Health Security Agency, a report was issued in which the agency stated that “a newly-designated delta sublineage as AY.4.2 has been observed expanding in England” while also confirming its monitoring of the subtype.

“This sublineage’s frequency is increasing. It also includes spike mutations A222V (Y145H). This sublineage was responsible for about 6% of all the sequences that were generated in week 27 September 2021, which is also the last week with full sequencing data. “This estimate is not exact… More assessment is being done,” the company noted.

Scott Gottlieb, former commissioner of the U.S. Food and Drug Administration, also tweeted at the weekend about the subtype.

Dr. Gottlieb explained that “U.K. recorded its largest single-day Covid cases increase in 3 month just as the new Delta variant AY.4 in the spike reaches 8 percent of UK sequenced patients.” Dr. Gottlieb stated that “we need urgent research to determine if this Delta plus is more transmissible and has partial immune Evasion.”

The delta subtype (also known as AY.4.2) is reported to be 10-15% more transmissibleIt is more common than the regular delta variant. However, it’s too early to know if it has caused an increase in cases in the U.K.

Danny Altmann (Professor of Immunology at Imperial College London) told CNBC Monday that this subtype needs to be closely monitored.

The hope was that delta might be represented because delta is now the dominant mutant across several regions, and has not been overtaken by any variants. [the]Maximum mutation performance possible by the virus. “AY.4 might be beginning to question this assertion,” he said.

Because the alpha variant of the virus first became known in Britain, it has been a leading strain worldwide. The U.K. was often seen as a sign of good things to follow.

It was the same with an even more dangerous variant of the virus, the delta version. This strain was initially discovered in India and then spread to the U.K.

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