Numerous attendees of the ETHDenver developers conference were affected by the transmissibility Omicron variant COVID-19. They reported experiencing symptoms and testing positive after the event.

Many social media posts from ETHDenver attendees after the conclusion of the Feb. 11–20 conference claim they tested positive for the virus. An article from a local newspaper reportedMore than 12,000 participants from over 100 countries were there, leading to many cases of infection among the unvaccinated as well.