Investing.com – U.S. stocks were lower after the close on Friday, as losses in the , and sectors led shares lower.

At the close in NYSE, the lost 0.48%, while the index fell 0.91%, and the index declined 0.91%.

The best performers of the session on the were Amgen Inc (NASDAQ:), which rose 0.93% or 2.02 points to trade at 219.38 at the close. Meanwhile, UnitedHealth Group Incorporated (NYSE:) added 0.80% or 3.32 points to end at 420.16 and American Express Company (NYSE:) was up 0.79% or 1.29 points to 163.92 in late trade.

Dow Inc (NYSE 🙂 fell 2.9% or 1.72 to trade at 56.75 at close. Caterpillar Inc (NYSE:) declined 1.89% or 3.85 points to end at 199.75 and Apple Inc (NASDAQ:) was down 1.83% or 2.73 points to 146.06.

The top performers on the S&P 500 were Thermo Fisher Scientific Inc (NYSE:) which rose 6.49% to 596.80, Invesco Plc (NYSE:) which was up 5.46% to settle at 26.25 and Centene Corp (NYSE:) which gained 4.95% to close at 64.64.

The worst performers were Unum Group (NYSE:) which was down 6.04% to 24.27 in late trade, International Flavors & Fragrances Inc (NYSE:) which lost 5.53% to settle at 135.21 and Copart Inc (NASDAQ:) which was down 5.46% to 143.95 at the close.

The top performers on the NASDAQ Composite were Corvus Pharmaceuticals Inc (NASDAQ:) which rose 135.40% to 5.320, Helbiz Inc (NASDAQ:) which was up 96.56% to settle at 17.69 and Priority Technology Holdings Inc (NASDAQ:) which gained 47.23% to close at 7.450.

The worst performers were Protagonist Therapeutics Inc (NASDAQ:) which was down 62.00% to 17.53 in late trade, Tcr2 Therapeutics Inc (NASDAQ:) which lost 36.45% to settle at 9.99 and Eliem Therapeutics Inc (NASDAQ:) which was down 21.92% to 18.77 at the close.

The New York Stock Exchange saw falling stocks surpassing advancing stock by 2032, 1163 to 17.53, 135 was unchanged, and Tcr2 Therapeutics Inc (NASDAQ) lost 36.45% to settle at 9.99. On the Nasdaq Stock Exchange 1901 rose, 1681 fell, while 154 was unchanged.

Thermo Fisher Scientific Inc. (NYSE:), shares rose to new highs, gaining 6.9% or 36.36 to 566.68.80. Corvus Pharmaceuticals Inc. shares (NASDAQ:) reached 52-week peak; an increase of 135.40%, or 3.060 to 5.320. Protagonist Therapeutics Inc. (NASDAQ:), shares fell to 52 week lows, down 62.00%. This is a decrease of 28.60 to 17.53. Helbiz Inc’s shares (NASDAQ:), rose to their highest levels ever, rising 96.56% to 8.69 to 17.69. Tcr2 Therapeutics Inc shares (NASDAQ:) dropped to 52 week lows, falling 36.45% (5.73 to 9.99).

The , which measures the implied volatility of S&P 500 options, was up 11.34% to 20.81.

The December delivery of Gold Futures was lower by 0.24%, or 4.15 to $1752.55 per troy ounce. In commodities trading, crude oil fell 0.64 or 0.88% to $71.92 per barrel in October. The November Brent oil contract dropped 0.36 or 0.48% to $75.31 per barrel.

EUR/USD fell 0.31% at 1.1728 while USD/JPY rose 0.2% to 109.98.

US Dollar Index Futures were up 0.3% at 93.213.